The Indian Journal of Biochemistry and Biophysics (IJBB), CSIR-National Institute of Science Communication and Policy Research (NIScPR), New Delhi, has brought out a special issue in association with Birla Institute of Technology and Sciences (BITS), Pilani, K K Birla Goa Campusand theSociety of Biological Chemists –India, (SBC-I) on the theme, “Biological Chemistry: Opportunities, Challenges and the Way Forward” . As a leading public funded Science publishing institute in India, CSIR-NIScPR publishes 15 journals in various STI disciplines, and all of them are indexed by reputed national/international agencies like Science Citation Index (Web of Science), Scopus, NAAS and UGC CARE.

IJBB, a monthly premier peer-reviewed research journal in the subject area of Biochemistry, Biophysics and Biotechnology, with the JIF score of 1.5. With reputed national/international experts on Board, the journal has been receiving considerable attention from researchers and academicians across the globe. Its commitment to publishing quality research makes it a vital resource for those seeking to stay at the forefront of these critical scientific disciplines. This special issue (March 2025 IJBB Vol. 62 Issue no. 3) has 9 review papers and 1 original research paper broadly covering the emerging trends in the Biological Chemistry contributed by reputed researchers in the subject area.

The articles cover (i) Phosphodiesterase 4 as a candidate therapeutic target of cancer (ii) A review on repurposing anti-diabetic drugs for the amelioration of betel-nut induced carcinogenesis; (iii) Chromatin higher order structure and possible therapeutic target (iv) From 2D to 3D: decoding tuberculosis pathobiology and drug development with ex vivo disease models; (v) Transport mediated antibiotic resistance in Mycobacterium tuberculosis; (vi) Phenotypic antibiotic resistance: Involvement of genes and additional factors; (vii) An overview of response pathways for protection of mitochondria from protein misfolding stress (viii) Advances in myogenic differentiation: Role of stem cells, RNA-binding proteins, molecular pathways, and detection Techniques; (ix) Aspergillusnigeracidogenic metabolism: A biased view from the C and N interface; and (x) Camptothecin exerts anti-cancer effects through FoxM1 inhibition

Publication of this special issue was possible only with the intensive effort of Prof. Ranjana Aggarwal, Director, CSIR-NIScPR, New Delhi, and able guidance of the Editorial Board comprising globally renowned experts Prof. Stephen Dimitrov (Chief Editor, IJBB), Prof DN Rao (Executive Editor, IJBB), Guest editors Prof. Suman Kundu and Prof. Meenal Kowshik, from BITS, Goa Campus, and the initiative taken by Dr. NK Prasanna, Editor, IJBB. We appreciate the kind encouragement from Dr Charu Verma, Head, Research Journals. Contribution from authors, reviewers, and the technical support provided by the print production team of CSIR-NIScPR for successful timely publication of this issue deserves special mention.

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NKR/PSM

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