Press Information Bureau
Government of India
Ministry of Health and Family Welfare
07-April-2011 17:44 IST
Reported NDM-1 not A Significant Problem: Min of H&FW
Regarding LANCET Article ‘Dissemination of NDM-1 Positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence’ published online on 6.04.2011, the official statement by Ministry of Health and Family Welfare, Government of India, is as follows:

• “The environmental presence of NDM-1 gene carrying bacteria is not a significant finding since there is no clinical or epidemiological linkage of this finding in the study area as given in the publication. The fact that patients respond well to medical & postsurgical antibiotic treatment indicates that NDM-1 is not a significant problem in the country.

• Infact in the same area the study carried out by Sir Ganga Ram Hospital, New Delhi shows that Esch.coli isolated from the gut of a large randomly selected sample of pregnant women did not show any carbapenem resistant Esch.coli in the stool samples indicating no presence of NDM1 .

• The carbapenem antibiotic is not required to be used in the treatment of Cholera & shigella dysentery as these cases respond to commonly used antibiotics.

• The publication itself mentions that NDM 1 gene is not a stable character in most of the isolates indicating that any time it can revert back to a sensitive state.

• Carbapenem resistance develops mainly in patients who are on carbapenem therapy. However Carbapenem is sparingly used under the supervision of doctor.

• The chlorination carried out for making water safe for drinking inactivates sensitive & drug resistant bacteria alike.

• Drug resistance surveillance is an ongoing activity in all major hospitals providing sentinel data.

The study is unsupported by any clinical & epidemiological evidence and also does not highlight the unstable character of the isolates.”